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Uncertainty Principle relates the uncertainty of a particle's position, Δx, and the uncertainty of a particle's momentum, Δp, and was formulated by Heisenberg in 1927.
( Δx)( Δp) ≥ h/(2π) where h is Planck's constant.
As a consequence of the wave-particle duality of matter, any attempt to determine the position of a particle affects the particle's momentum. The more certain we are of either one of a particle's momentum or position, the less certain we can be of the other.